Higashida H, Munesue T, Kosaka H, Yamasue H, Yokoyama S, Kikuchi M. Social Interaction Improved by Oxytocin in the Subclass of Autism with Comorbid Intellectual Disabilities. Diseases. 2019 Feb 22;7(1).
Iwashiro N, Takano Y, Natsubori T, Aoki Y, Yahata N, Gonoi W, Kunimatsu A, Abe O, Kasai K, Yamasue H*. Aberrant attentive and inattentive brain activity to auditory negative words, and its relation to persecutory delusion in patients with schizophrenia. Neuropsychiatr Dis Treat. 2019 Feb 14;15:491-502.
2018(*責任著者)
Yamasue H*, Okada T, Munesue T, Kuroda M, Fujioka T, Uno Y, Matsumoto K, Kuwabara H, Mori D, Okamoto Y, Yoshimura Y, Kawakubo Y, Arioka Y, Kojima M, Yuhi T, Owada K, Yassin W, Kushima I, Benner S, Ogawa N, Eriguchi Y, Kawano N, Uemura Y, Yamamoto M, Kano Y, Kasai K, Higashida H, Ozaki N, Kosaka H. Effect of intranasal oxytocin on the core social symptoms of autism spectrum disorder: A randomized clinical trial. Mol Psychiatry. 2018 Jun 29. doi: 10.1038/s41380-018-0097-2. [Epub ahead of print].
Benner S, Aoki Y, Watanabe T, Endo N, Abe O, Kuroda M, Kuwabara H, Kawakubo Y, Takao H, Kunimatsu A, Kasai K, Bito H, Kakeyama M, Yamasue H: Neurochemical evidence for differential effects of acute and repeated oxytocin administration, Mol Psychiatry, 2018. [Epub ahead of print]
Matsunaga M, Masuda T, Ishii K, Ohtsubo Y, Noguchi Y, Ochi M, Yamasue H. Culture and cannabinoid receptor gene polymorphism interact to influence the perception of happiness. PLoS One. 2018 Dec 21;13(12):e0209552. doi: 10.1371/journal.pone.0209552.
Kushima I, Aleksic B, Nakatochi M, Shimamura T, Okada T, Uno Y, Morikawa M, Ishizuka K, Shiino T, Kimura H, Arioka Y, Yoshimi A, Takasaki Y, Yu Y, Nakamura Y, Yamamoto M, Iidaka T, Iritani Shuji, Inada T, Ogawa N, Shishido E, Torii Youta, Kawano N, Omura Y, Yoshikawa T, Uchiyama T, Yamamoto T, Ikeda M, Hashimoto R, Yamamori H, Yasuda Y, Someya T, Watanabe Y, Egawa J, Nunokawa A, Itokawa M, Arai M, Miyashita M, Kobori A, Suzuki M, Takahashi T, Usami M, Kodaira M, Watanabe K, Sasaki T, Kuwabara H, Tochigi M, Nishimura F, Yamasue H, Eriguchi Y, Benner S, Kojima M, Yassin W, Munesue T, Yokoyama S, Kimura R, Funabiki Y, Kosaka H, Ishitobi M, Ohmori T, Numata S, Yoshikawa T, Toyota T, Yamakawa K, Suzuki T, Inoue Y, Nakaoka K, Goto Y, Inagaki M, Hashimoto N, Kusumi I, Son S, Murai T, Ikegame T, Okada N, Kasai K, Kunimoto S, Mori D, Iwata N, Ozaki N. Comparative analyses of copy number variation in autism spectrum disorder and schizophrenia reveal etiological overlap and biological insights. Cell Reports. 9th Aug 2018 accepted
Ikeda M, Takahashi A, Kamatani Y, Momozawa Y, Saito T, Kondo K, Shimasaki A, Kawase K, Sakusabe T, Iwayama Y, Toyota T, Wakuda T, Kikuchi M, Kanahara N, Yamamori H, Yasuda Y, Watanabe Y, Hoya S, Aleksic B, Kushima I, Arai H, Takaki M, Hattori K, Kunugi H, Okahisa Y, Ohnuma T, Ozaki N, Someya T, Hashimoto R, Yoshikawa T, Kubo M, Iwata N. Genome-Wide Association Study Detected Novel Susceptibility Genes for Schizophrenia and Shared Trans-Populations/Diseases Genetic Effect. Schizophr Bull. Oct 3. doi: 10.1093/schbul/sby140. 2018.
Kojima M, Yassin W, Owada K, Aoki Y, Kuwabara H, Natsubori T, Iwashiro N, Gonoi W, Takao H, Kasai K, Abe O, Kano Y, Yamasue H*. Neuroanatomical Correlates of Advanced Paternal and Maternal Age at Birth in Autism Spectrum Disorder. Cereb Cortex. 2018 May 25. doi: 10.1093/cercor/bhy122. [Epub ahead of print]
Benner S, Yamasue H*. Clinical potential of oxytocin in autism spectrum disorder: current issues and future perspectives. Behav Pharmacol. 2018 Feb;29(1):1-12.
Yamasue H*, Domes G. Oxytocin and Autism Spectrum Disorders. Curr Top Behav Neurosci. 2017 Aug 2.
Nakaizumi K, Ouchi Y, Terada T, Yoshikawa E, Kakimoto A, Isobe T, Bunai T, Yokokura M, Suzuki K, Magata Y.: In vivo depiction of α7 nicotinic receptor loss for cognitive decline in Alzheimer's disease. J Alzheimers Dis. 61(4):1355-1365, 2018.
Bunai T, Terada T, Kono S, Yokokura M, Yoshikawa E, Futatsubashi M, Miyajima H, Ouchi Y.: Neuroinflammation following disease modifying therapy in multiple sclerosis: A pilot positron emission tomography study. J Neurol Sci. 15;385:30-33, 2018.
Owada K, Kojima M, Yassin W, Kuroda M, Kawakubo Y, Kuwabara H, Kano Y, Yamasue H*. Computer-analyzed facial expression as a surrogate marker for autism spectrum social core symptoms. PLoS One. 2018 Jan 2;13(1):e0190442.
Nakamura M, Takahashi T, Takayanagi Y, Sasabayashi D, Katagiri N, Sakuma A, Obara C, Koike S, Yamasue H, Furuichi A, Kido M, Nishikawa Y, Noguchi K, Matsumoto K, Mizuno M, Kasai K, Suzuki M.Surface morphology of the orbitofrontal cortex in individuals at risk of psychosis: a multicenter study. Eur Arch Psychiatry Clin Neurosci. 2018 Mar 23.
2017
Matsunaga M, Kawamichi H, Umemura T, Hori R, Shibata E, Kobayashi F, Suzuki K, Ishii K, Ohtsubo Y, Noguchi Y, Ochi M, Yamasue H, Ohira H. Neural and Genetic Correlates of the Social Sharing of Happiness. Front Neurosci. 2017;11:718.
Sasabayashi D, Takayanagi Y, Takahashi T, Koike S, Yamasue H, Katagiri N, Sakuma A, Obara C, Nakamura M, Furuichi A, Kido M, Nishikawa Y, Noguchi K, Matsumoto K, Mizuno M, Kasai K, Suzuki M. Increased occipital gyrification and development of psychotic disorders in individuals with an at-risk mental state: a multicenter study. Biological Psychiatry, 2017;82:737-745.
Matsunaga M, Ishii K, Ohtsubo Y, Noguchi Y, Ochi M, Yamasue H. Association between salivary serotonin and the social sharing of happiness. PLOS ONE, 2017;12(7):e0180391.
Hashimoto N, Ito YM, Okada N, Yamamori H, Yasuda Y, Fujimoto M, Kudo N, Takemura A, Son S, Narita H, Yamamoto M, Tha KK, Katsuki A, Ohi K, Yamashita F, Koike S, Takahashi T, Nemoto K, Fukunaga M, Onitsuka T, Watanabe Y, Yamasue H, Suzuki M, Kasai K, Kusumi I, Hashimoto R. The effect of duration of illness and antipsychotics on subcortical volumes in schizophrenia: Analysis of 778 subjects. Neuroimage Clin. 2017;17:563-569.
Paparelli A, Iwata K, Wakuda T, Iyegbe C, Murray RM, Takei N. Perinatal Asphyxia in Rat Alters Expression of Novel Schizophrenia Risk Genes. Front Mol Neurosci. 10:341, 2017.
Fukai M, Hirosawa T, Kikuchi M, Ouchi Y, Takahashi T, Yoshimura Y, Miyagishi Y, Kosaka H, Yokokura M, Yoshikawa E, Bunai T, Minabe Y.: Oxytocin effects on emotional response to others' faces via serotonin system in autism: A pilot study. Psychiatry Res. Jun 28;267:45-50, 2017
Balan S, Kameno Y: Comprehensive association analysis of 27 genes from the GABAergic system in Japanese individuals affected with schizophrenia., Schizophr Res., 185, 33-40. 2017.
Yokokura M, Terada T, Bunai T, Nakaizumi K, Takebayashi K, Iwata Y, Yoshikawa E, Futatsubashi M, Suzuki K, Mori N, Ouchi Y: Depiction of microglial activation in aging and dementia: Positron emission tomography with [11C]DPA713 versus [11C](R)PK11195. J Cereb Blood Flow Metab 37(3): 877-889, 2017.
Takano Y, Aoki Y, Yahata N, Kawakubo Y, Inoue H, Iwashiro N, Natsubori T, Koike S, Gonoi W, Sasaki H, Takao H, Kasai K, Yamasue H*. Neural basis for inferring false beliefs and social emotions in others among individuals with schizophrenia and those at ultra-high risk for psychosis. Psychiatry Research: Neuroimaging 2017; 259:34-41.
Watanabe T, Otowa T, Abe O, Kuwabara H, Aoki Y, Natsubori T, Takao H, Kakiuchi C, Kondo K, Ikeda M, Iwata N, Kasai K, Sasaki T, Yamasue H*. Oxytocin receptor gene variations predict neural and behavioral response to oxytocin in autism. Social Cognitive and Affective Neuroscience 2017;12(3):496-506.
Balan S, Yamada K, Iwayama Y, Hashimoto T, Toyota T, Shimamoto C, Maekawa M, Takagai S, Wakuda T, Kameno Y, Kurita D, Yamada K, Kikuchi M, Hashimoto T, Kanahara N, Yoshikawa T. Comprehensive association analysis of 27 genes from the GABAergic system in Japanese individuals affected with schizophrenia. Schizophr Res.pii: S0920-9964(17)30003-8. 2017.
Hirosawa T, Kikuchi M, Ouchi Y, Takahashi T, Yoshimura Y, Kosaka H, Furutani N, Hiraishi H, Fukai M, Yokokura M, Yoshikawa E, Bunai T, Minabe Y: A pilot study of serotonergic modulation after long-term administration of oxytocin in autism spectrum disorder. Autism Res. 2017 Mar 7 [Epub ahead of print]
2016
Kameno Y, Suzuki K, Takagai S, Iwata K, Matsuzaki H, Takahashi K, Wakuda T, Iwata Y, Magata Y, Mori N: Mismatch in cerebral blood flow and glucose metabolism after the forced swim stress in rats., Acta Neuropsychiatr, 28, 6, 352-356, 2016.
Terada T, Yokokura M, Yoshikawa E, Futatsubashi M, Kono S, Konishi T, Miyajima H, Hashizume T, Ouchi Y: Extrastriatal spreading of microglial activation in Parkinson's disease: a positron emission tomography study. Ann Nucl Med 30(8): 579-587, 2016
Kosaka H, Okamoto Y, Munesue T, Yamasue H, Inohara K, Fujioka T, Anme T, Orisaka M, Ishitobi M, Jung M, Fujisawa T, Tanaka S, Arai S, Asano M, Saito D, Sadato N, Tomoda A, Omori M, Sato M, Okazawa H, Higashida H, Wada Y. Oxytocin efficacy is modulated by dosage and oxytocin receptor genotype in young adults with high-functioning autism: A 24-week randomized clinical trial. Transl Psychiatry 2016;6(8):e872.
Okada N, Fukunaga M, Yamashita F, Koshiyama D, Yamamori H, Isobe M, Isomura S, Natsubori T, Narita H, Hashimono N, Miyata J, Koike S, Takahashie T, Yamasue H, Matsuo K, Onitsuka T, Iidaka T, Kawasaki Y, Yoshimura R, Watanabe Y, Suzuki M, Turner JA, Takeda M, Thompson PM, Osaki N, Kasai K, Hashimoto R. Abnomal asymmertries in subcorticl brain volume in schizophrenia. Mol Psychiatry. 2016;21(10):1460-6.
Fujioka T, Inohara K, Okamoto Y, Masuya Y, Ishitobi M, Saito DN, Jung M, Arai S, Matsumura Y, Fujisawa TX, Narita K, Suzuki K, Tsuchiya KJ, Mori N, Katayama T, Sato M, Munesue T, Okazawa H, Tomoda A, Wada Y, Kosaka H*: Gazefinder as a clinical supplementary tool for discriminating between autism spectrum disorder and typical development in male adolescents and adults, Mol Autism, 7:19, 2016.
Nishimura T, Takei N*, Tsuchiya KJ, Asano R, Mori N: Identification of neurodevelopmental trajectories in infancy and of risk factors affecting deviant development: a longitudinal birth cohort study, Int J Epidemiol, pii:dyv363, 2016.
Liu X, Shimada T, Otowa T, Wu YY, Kawamura Y, Tochigi M, Iwata Y, Umekage T, Toyota T, Maekawa M, Iwayama Y, Suzuki K, Kakiuchi C, Kuwabara H, Kano Y, Nishida H, Sugiyama T, Kato N, Chen CH, Mori N, Yamada K, Yoshikawa T, Kasai K, Tokunaga K, Sasaki T*, Gau SS*: Genome-wide association study of autism spectrum disorder in the east asian populations, Autism Res, 9:340-349, 2016.
Tang Y, Han S, Asakawa T, Luo Y, Han X, Xiao B, Dong Q, Lu C, Wang L*: Effects of intracerebral hemorrhage on 5-hydroxymethylcytosine modification in mouse brain, Neuropsychiatr Dis Treat, 12:617-624, 2016.
2015
Inoue J, Hoshino R, Nojima H, Ishida W and Okamoto N: Additional donepezil treatment for patients with geriatric depression who exhibit cognitive deficit during treatment for depression, Psychogeriatrics, 16: 54-61, 2015.
Takagai S, Tsuchiya KJ*, Itoh H, Kanayama N, Mori N, Takei N: Cohort profile: Hamamatsu Birth Cohort for Mothers and Children (HBC Study), Int J Epidemiol, 5(2):333-42., 2015.
Maekawa M, Iwayama Y, Ohnishi T, Toyoshima M, Shimamoto C, Hisano Y, Toyota T, Balan S, Matsuzaki H, Iwata Y, Takagai S, Yamada K, Ota M, Fukuchi S, Okada Y, Akamatsu W, Tsujii M, Kojima N, Owada Y, Okano H, Mori N, Yoshikawa T*: Investigation of the fatty acid transporter-encoding genes SLC27A3 and SLC27A4 in autism, Sci Rep, 5:16239, 2015.
Yamada K, Hattori E, Iwayama Y, Toyota T, Iwata Y, Suzuki K, Kikuchi M, Hashimoto T, Kanahara N, Mori N, Yoshikawa T*: Population-dependent contribution of the major histocompatibility complex region to schizophrenia susceptibility. Schizophr Res, 168:444-449, 2015.
Miyaoka T*, Furuya M, Horiguchi J, Wake R, Hashioka S, Thoyama M, Murotani K, Mori N, Minabe Y, Iyo M, Ueno S, Ezoe S, Hoshino S, Seno H: Efficacy and safety of yokukansan in treatment-resistant schizophrenia: a randomized, multicenter, double-blind, placebo-controlled trial, Evid Based Complement Alternat Med, 2015:201592, 2015.
Yamagishi S*, Yamada K, Sawada M, Nakano S, Mori N, Sawamoto K, Sato K: Netrin-5 is highly expressed in neurogenic regions of the adult brain, Front Cell Neurosci, 9:146, 2015.
Shimamoto C, Ohnishi T, Maekawa M, Watanabe A, Ohba H, Arai R, Iwayama Y, Hisano Y, Toyota T, Toyoshima M, Suzuki K, Shirayama Y, Nakamura K, Mori N, Owada Y, Kobayashi T, Yoshikawa T*: Functional characterization of FABP3, 5 and 7 gene variants identified in schizophrenia and autism spectrum disorder and mouse behavioral studies, Hum Mol Genet, 24:2409, 2015.
Bangel FN, Yamada K, Arai M, Iwayama Y, Balan S, Toyota T, Iwata Y, Suzuki K, Kikuchi M, Hashimoto T, Kanahara N, Mori N, Itokawa M, Stork O, Yoshikawa T*: Genetic analysis of the glyoxalase system in schizophrenia, Prog Neuropsychopharmacol Biol Psychiatry, 59:105-110, 2015.
Maekawa M, Yamada K, Toyoshima M, Ohnishi T, Iwayama Y, Shimamoto C, Toyota T, Nozaki Y, Balan S, Matsuzaki H, Iwata Y, Suzuki K, Miyashita M, Kikuchi M, Kato M, Okada Y, Akamatsu W, Mori N, Owada Y, Itokawa M, Okano H, Yoshikawa T*: Utility of scalp hair follicles as a novel source of biomarker genes for psychiatric illnesses, Biol Psychiatry, 78:116-125, 2015.
Jitoku D, Yamamoto N, Iwayama Y, Toyota T, Miyagi M, Enokida T, Tasaka Y, Umino M, Umino A, Uezato A, Iwata Y, Suzuki K, Kikuchi M, Hashimoto T, Kanahara N, Kurumaji A, Yoshikawa T, Nishikawa T*: Association study of H2AFZ with schizophrenia in a Japanese case-control sample, J Neural Transm (Vienna), 122:915-923, 2015.
Wakuda T, Iwata K, Iwata Y, Anitha A, Takahashi T, Yamada K, Vasu MM, Matsuzaki H, Suzuki K, Mori N: Perinatal asphyxia alters neuregulin-1 and COMT gene expression in the medial prefrontal cortex in rats. Prog Neuropsychopharmacol Biol Psychiatry. 2;56:149-154, 2015.
Wakusawa K, Sugiura M, Sassa Y, Jeong H, Yomogida Y, Horie K, Sato S, Yokoyama H, Kure S, Takei N, Mori N, Kawashima R: Adaptive ability to cope with atypical or novel situations involving tool use: An fMRI approach. Neurosci Res. 90:72-82 2015.
2014
Balan S, Iwayama Y, Maekawa M, Toyota T, Ohnishi T, Toyoshima M, Shimamoto C, Esaki K, Yamada K, Iwata Y, Suzuki K, Ide M, Ota M, Fukuchi S, Tsujii M, Mori N, Shinkai Y, Yoshikawa T: Exon resequencing of H3K9 methyltransferase complex genes, EHMT1, EHTM2 and WIZ, in Japanese autism subjects. Mol Autism. 5:49,2014.
Mundalil Vasu M, Anitha A, Thanseem I, Suzuki K, Yamada K, Takahashi T, Wakuda T, Iwata K, Tsujii M, Sugiyama T, Mori N: Serum microRNA profiles in children with autism. Mol Autism. 5:40, 2014.
Shimamoto C, Ohnishi T, Maekawa M, Watanabe A, Ohba H, Arai R, Iwayama Y, Hisano Y, Toyota T, Toyoshima M, Suzuki K, Shirayama Y, Nakamura K, Mori N, Owada Y, Kobayashi T, Yoshikawa T: Functional characterization of FABP3, 5 and 7 gene variants identified in schizophrenia and autism spectrum disorder and mouse behavioral studies. Hum Mol Genet. 23:6495-6511, 2014.
Miyaoka T, Furuya M, Horiguchi J, Wake R, Hashioka S, Tohyama M, Mori N, Minabe Y, Iyo M, Ueno S, Ezoe S, Murotani K, Hoshino S, Seno H: Efficacy and safety of yokukansan in treatment-resistant schizophrenia: a randomized, double-blind, placebo-controlled trial (a Positive and Negative Syndrome Scale, five-factor analysis). Psychopharmacology. 2014 Jun 13. [Epub ahead of print]
Anitha A, Thanseem I, Nakamura K, Vasu MM, Yamada K, Ueki T, Iwayama Y, Toyota T, Tsuchiya KJ, Iwata Y, Suzuki K, Sugiyama T, Tsujii M, Yoshikawa T, Mori N: Zinc finger protein 804A (ZNF804A) and verbal deficits in individuals with autism. J Psychiatry Neurosci. 39:294-303, 2014.
Iwata K, Matsuzaki H, Tachibana T, Ohno K, Yoshimura S, Takamura H, Yamada K, Matsuzaki S, Nakamura K, Tsuchiya KJ, Matsumoto K, Tsujii M, Sugiyama T, Katayama T, Mori N: N-ethylmaleimide-sensitive factor interacts with the serotonin transporter and modulates its trafficking: implications for pathophysiology in autism. Mol Autism. 5:33, 2014.
Muramatsu-Kato K, Itoh H, Kobayashi-Kohmura Y, Murakami H, Uchida T, Suzuki K, Sugihara K, Kanayama N, Tsuchiya KJ, Takei N.: Hamamatsu Birth Cohort (HBC) Study Team. Comparison between placental gene expression of 11β-hydroxysteroid dehydrogenases and infantile growth at 10 months of age. Journal of Obstetric and Gynaecology Research 40:465-72, 2014.
2013
Kameno Y, Iwata K, Matsuzaki H, Miyachi T, Tsuchiya KJ, Matsumoto K, Iwata Y, Suzuki K, Nakamura K, Maekawa M, Tsujii M, Sugiyama T, Mori N: Serum levels of soluble platelet endothelial cell adhesion molecule-1 and vascular cell adhesion molecule-1 are decreased in subjects with autism spectrum disorder. Mol Autism. 4(1):19, 2013.
Balan S, Yamada K, Hattori E, Iwayama Y, Toyota T, Ohnishi T, Maekawa M, Toyoshima M, Iwata Y, Suzuki K, Kikuchi M, Yoshikawa T*: Population-specific haplotype association of the postsynaptic density gene DLG4 with schizophrenia, in family-based association studies. PLoS One. 8:e70302, 2013.
Balan S, Yamada K, Iwayama Y, Toyota T, Ohnishi T, Maekawa M, Toyoshima M, Iwata Y, Suzuki K, Kikuchi M, Ujike H, Inada T, Kunugi H, Ozaki N, Iwata N, Nanko S, Kato T, Yoshikawa T*: Lack of association of EGR2 variants with bipolar disorder in Japanese population. Gene. 526:246-250, 2013.
Suzuki K, Sugihara G, Ouchi Y, Nakamura K, Futatsubashi M, Takebayashi K, Yoshihara Y, Omata K, Matsumoto K, Tsuchiya KJ, Iwata Y, Tsujii M, Sugiyama T, Mori N. Microglial activation in young adults with autism spectrum disorder. JAMA Psychiatry. 70(1):49-58, 2013.
Tsuchiya KJ, Matsumoto K, Yagi A, Inada N, Kuroda M, Inokuchi E, Koyama T, Kamio Y, Tsujii M, Sakai S, Mohri I, Taniike M, Iwanaga R, Ogasahara K, Miyachi T, Nakajima S, Tani I, Ohnishi M, Inoue M, Nomura K, Hagiwara T, Uchiyama T, Ichikawa H, Kobayashi S, Miyamoto K, Nakamura K, Suzuki K, Mori N, Takei N. Reliability and validity of autism diagnostic interview-revised, Japanese version. J Autism Dev Disord. 43(3):643-62, 2013.
Anitha A, Nakamura K, Thanseem I, Matsuzaki H, Miyachi T, Tsujii M, Iwata Y, Suzuki K, Sugiyama T, Mori N. Downregulation of the expression of mitochondrial electron transport complex genes in autism brains. Brain Pathol. ;23(3):294-302, 2013.
Shimmura C, Suzuki K, Iwata Y, Tsuchiya KJ, Ohno K, Matsuzaki H, Iwata K, Kameno Y, Takahashi T, Wakuda T, Nakamura K, Hashimoto K, Mori N. Enzymes in the glutamate-glutamine cycle in the anterior cingulate cortex in postmortem brain of subjects with autism. Mol Autism. 4(1):6, 2013.
Takata A, Iwayama Y, Fukuo Y, Ikeda M, Okochi T, Maekawa M, Toyota T, Yamada K, Hattori E, Ohnishi T, Toyoshima M, Ujike H, Inada T, Kunugi H, Ozaki N, Nanko S, Nakamura K, Mori N, Kanba S, Iwata N, Kato T, Yoshikawa T. A population-specific uncommon variant in GRIN3A associated with schizophrenia. Biol Psychiatry. 73(6):532-9, 2013.
2012
Thanseem I, Anitha A, Nakamura K, Suda S, Iwata K, Matsuzaki H, Ohtsubo M, Ueki T, Katayama T, Iwata Y, Suzuki K, Minoshima S, Mori N. Elevated transcription factor Sp1 in autism brains alters the expression of autism candidate genes. Biol Psychiat 71:410-418; 2012.
Tsuchiya KJ, Tsutsumi H, Matsumoto K, Takei N, Narumiya M, Honda M, Thanseem I, Anitha A, Suzuki K, Matsuzaki H, Iwata Y, Nakamura K, Mori N; H. B. C. Study Team. Seasonal variations of neuromotor development by 14 months of age: Hamamatsu Birth Cohort for mothers and children (HBC Study). PLoS One. 7(12):e52057, 2012.
Anitha A, Nakamura K, Thanseem I, Yamada K, Iwayama Y, Toyota T, Matsuzaki H, Miyachi T, Yamada S, Tsujii M, Tsuchiya KJ, Matsumoto K, Iwata Y, Suzuki K, Ichikawa H, Sugiyama T, Yoshikawa T, Mori N. Brain region-specific altered expression and association of mitochondria-related genes in autism. Mol Autism. 3(1):12, 2012.
Iwata K, Izumo N, Matsuzaki H, Manabe T, Ishibashi Y, Ichitani Y, Yamada K, Thanseem I, Anitha A, Vasu MM, Shimmura C, Wakuda T, Kameno Y, Takahashi T, Iwata Y, Suzuki K, Nakamura K, Mori N. Vldlr overexpression causes hyperactivity in rats. Mol Autism. 3(1):11, 2012.
Takahashi S, Tsuchiya KJ, Matsumoto K, Suzuki K, Mori N, Takei N; HBC Study Team. Psychosocial determinants of mistimed and unwanted pregnancy: the Hamamatsu Birth Cohort (HBC) study. Matern Child Health J. 16(5):947-55, 2012.
Thanseem I, Anitha A, Nakamura K, Suda S, Iwata K, Matsuzaki H, Ohtsubo M, Ueki T, Katayama T, Iwata Y, Suzuki K, Minoshima S, Mori N. Elevated transcription factor specificity protein 1 in autistic brains alters the expression of autism candidate genes. Biol Psychiatry.71(5):410-8, 2012.
2011
Nakamura K, Iwata Y, Anitha A, Miyachi T, Toyota T, Yamada S, Tsujii M, Tsuchiya KJ, Iwayama Y, Yamada K, Hattori E, Matsuzaki H, Matsumoto K, Suzuki K, Suda S, Takebayashi K, Takei N, Ichikawa H, Sugiyama T, Yoshikawa T, Mori N. Replication study of Japanese cohorts supports the role of STX1A in autism susceptibility. Prog Neuropsychopharmacol Biol Psychiatry.32(2):454-458, 2011.
Takata A, Kim SH, Ozaki N, Iwata N, Kunugi H, Inada T, Ujike H, Nakamura K, Mori N, Ahn YM, Joo EJ, Song JY, Kanba S, Yoshikawa T, Kim YS, Kato T. Association of ANK3 with bipolar disorder confirmed in East Asia. Am J Med Genet B Neuropsychiatr Genet. 156(3):312-315, 2011.
Suzuki K, Sugihara G, Ouchi Y, Nakamura K, Tsujii M, Futatsubashi M, Iwata Y, Tsuchiya KJ, Matsumoto K, Takebayashi K, Wakuda T, Yoshihara Y, Suda S, Kikuchi M, Takei N, Sugiyama T, Irie T, Mori N. Reduced acetylcholinesterase activity in the fusiform gyrus in adults with autism spectrum disorders. Arch Gen Psychiatry. 68(3):306-313, 2011.
Iwata Y, Suzuki K, Takei N, Toulopoulou T, Tsuchiya KJ, Matsumoto K, Takagai S, Oshiro M, Nakamura K, Mori N. Jiko-shisen-kyofu (fear of one's own glance), but not taijin-kyofusho (fear of interpersonal relations), is an east Asian culture-related specific syndrome. Aust N Z J Psychiatry. 45(2):148-52, 2011.
Yokokura M, Mori N, Yagi S, Yoshikawa E, Kikuchi M, Yoshihara Y, Wakuda T, Sugihara G, Takebayashi K, Suda S, Iwata Y, Ueki T, Tsuchiya KJ, Suzuki K, Nakamura K, Ouchi Y. In vivo changes in microglial activation and amyloid deposits in brain regions with hypometabolism in Alzheimer's disease. Eur J Nucl Med Mol Imaging. 38(2):343-51, 2011.
2010
Thanseem I, Nakamura K, Miyachi T, Toyota T, Yamada S, Tsujii M, Tsuchiya KJ, Anitha A, Iwayama Y, Yamada K, Hattori E, Matsuzaki H, Matsumoto K, Iwata Y, Suzuki K, Suda S, Kawai M, Sugihara G, Takebayashi K, Takei N, Ichikawa H, Sugiyama T, Yoshikawa T, Mori N. Further evidence for the role of MET in autism susceptibility. Neurosci Res. 68(2):137-41, 2010.
Katoh Y, Uchida S, Kawai M, Takei N, Mori N, Kawakami J, Kagawa Y, Yamada S, Namiki N, Hashimoto H. Onset of clinical effects and plasma concentration of fluvoxamine in Japanese patients. Biol Pharm Bull. 33(12):1999-2002, 2010.
Arai M, Yuzawa H, Nohara I, Ohnishi T, Obata N, Iwayama Y, Haga S, Toyota T, Ujike H, Arai M, Ichikawa T, Nishida A, Tanaka Y, Furukawa A, Aikawa Y, Kuroda O, Niizato K, Izawa R, Nakamura K, Mori N, Matsuzawa D, Hashimoto K, Iyo M, Sora I, Matsushita M, Okazaki Y, Yoshikawa T, Miyata T, Itokawa M. Enhanced carbonyl stress in a subpopulation of schizophrenia. Arch Gen Psychiatry. 67(6):589-97, 2010.
Suzuki K, Iwata Y, Matsuzaki H, Anitha A, Suda S, Iwata K, Shinmura C, Kameno Y, Tsuchiya KJ, Nakamura K, Takei N, Mori N. Reduced expression of apolipoprotein E receptor type 2 in peripheral blood lymphocytes from patients with major depressive disorder. Prog Neuropsychopharmacol Biol Psychiatry. 34(6):1007-10, 2010.
Iwata Y, Yamada K, Iwayama Y, Anitha A, Thanseem I, Toyota T, Hattori E, Ohnishi T, Maekawa M, Nakamura K, Suzuki K, Matsuzaki H, Tsuchiya KJ, Suda S, Sugihara G, Takebayashi K, Yamamoto S, Iwata K, Mori N, Yoshikawa T. Failure to confirm genetic association of the FXYD6 gene with schizophrenia: the Japanese population and meta-analysis. Am J Med Genet B Neuropsychiatr Genet. 153B(6):1221-7, 2010.
Munesue T, Yokoyama S, Nakamura K, Anitha A, Yamada K, Hayashi K, Asaka T, Liu HX, Jin D, Koizumi K, Islam MS, Huang JJ, Ma WJ, Kim UH, Kim SJ, Park K, Kim D, Kikuchi M, Ono Y, Nakatani H, Suda S, Miyachi T, Hirai H, Salmina A, Pichugina YA, Soumarokov AA, Takei N, Mori N, Tsujii M, Sugiyama T, Yagi K, Yamagishi M, Sasaki T, Yamasue H, Kato N, Hashimoto R, Taniike M, Hayashi Y, Hamada J, Suzuki S, Ooi A, Noda M, Kamiyama Y, Kido MA, Lopatina O, Hashii M, Amina S, Malavasi F, Huang EJ, Zhang J, Shimizu N, Yoshikawa T, Matsushima A, Minabe Y, Higashida H. Two genetic variants of CD38 in subjects with autism spectrum disorder and controls. Neurosci Res. 67(2):181-91, 2010.
Kushima I, Aleksic B, Ito Y, Nakamura Y, Nakamura K, Mori N, Kikuchi M, Inada T, Kunugi H, Nanko S, Kato T, Yoshikawa T, Ujike H, Suzuki M, Iwata N, Ozaki N. Association study of ubiquitin-specific peptidase 46 (USP46) with bipolar disorder and schizophrenia in a Japanese population. J Hum Genet. 55(3):133-6, 2010.
Fujita-Shimizu A, Suzuki K, Nakamura K, Miyachi T, Matsuzaki H, Kajizuka M, Shinmura C, Iwata Y, Suda S, Tsuchiya KJ, Matsumoto K, Sugihara G, Iwata K, Yamamoto S, Tsujii M, Sugiyama T, Takei N, Mori N. Decreased serum levels of adiponectin in subjects with autism. Prog Neuropsychopharmacol Biol Psychiatry. 34(3):455-8, 2010.
Maekawa M, Iwayama Y, Arai R, Nakamura K, Ohnishi T, Toyota T, Tsujii M, Okazaki Y, Osumi N, Owada Y, Mori N, Yoshikawa T. Polymorphism screening of brain-expressed FABP7, 5 and 3 genes and association studies in autism and schizophrenia in Japanese subjects. J Hum Genet. 55(2):127-30, 2010.
Suzuki K, Nishimura K, Sugihara G, Nakamura K, Tsuchiya KJ, Matsumoto K, Takebayashi K, Isoda H, Sakahara H, Sugiyama T, Tsujii M, Takei N, Mori N. Metabolite alterations in the hippocampus of high-functioning adult subjects with autism. Int J Neuropsychopharmacol. 13(4):529-34, 2010.
Katoh Y, Uchida S, Kawai M, Takei N, Mori N, Kawakami J, Kagawa Y, Yamada S, Namiki N, Hashimoto H. Effects of cigarette smoking and cytochrome P450 2D6 genotype on fluvoxamine concentration in plasma of Japanese patients. Biol Pharm Bull. 33(2):285-8, 2010.
Kajizuka M, Miyachi T, Matsuzaki H, Iwata K, Shinmura C, Suzuki K, Suda S, Tsuchiya KJ, Matsumoto K, Iwata Y, Nakamura K, Tsujii M, Sugiyama T, Takei N, Mori N. Serum levels of platelet-derived growth factor BB homodimers are increased in male children with autism. Prog Neuropsychopharmacol Biol Psychiatry. 34(1):154-8, 2010.
Nakamura K, Sekine Y, Ouchi Y, Tsujii M, Yoshikawa E, Futatsubashi M, Tsuchiya KJ, Sugihara G, Iwata Y, Suzuki K, Matsuzaki H, Suda S, Sugiyama T, Takei N, Mori N. Brain serotonin and dopamine transporter bindings in adults with high-functioning autism. Arch Gen Psychiatry. 67(1):59-68, 2010.
2009
Watanabe T, Ogai Y, Koga T, Senoo E, Nakamura K, Mori N, Ikeda K. Assessment of Japanese stimulant control law offenders using the Addiction Severity Index--Japanese version: comparison with patients in treatment settings. Int J Environ Res Public Health. 6(12):3056-69, 2009.
Takahashi T, Zhu Y, Hata T, Shimizu-Okabe C, Suzuki K, Nakahara D. Intracranial self-stimulation enhances neurogenesis in hippocampus of adult mice and rats. Neuroscience. 158(2):402-411, 2009.
Maekawa M, Iwayama Y, Nakamura K, Sato M, Toyota T, Ohnishi T, Yamada K, Miyachi T, Tsujii M, Hattori E, Maekawa N, Osumi N, Mori N, Yoshikawa T. A novel missense mutation (Leu46Val) of PAX6 found in an autistic patient. Neurosci Lett. 462(3):267-71, 2009.
Nakamura K, Sekine Y, Takei N, Iwata Y, Suzuki K, Anitha A, Inada T, Harano M, Komiyama T, Yamada M, Iwata N, Iyo M, Sora I, Ozaki N, Ujike H, Mori N. An association study of monoamine oxidase A (MAOA) gene polymorphism in methamphetamine psychosis. Neurosci Lett. 455(2):120-3, 2009.
Hattori E, Toyota T, Ishitsuka Y, Iwayama Y, Yamada K, Ujike H, Morita Y, Kodama M, Nakata K, Minabe Y, Nakamura K, Iwata Y, Takei N, Mori N, Naitoh H, Yamanouchi Y, Iwata N, Ozaki N, Kato T, Nishikawa T, Kashiwa A, Suzuki M, Shioe K, Shinohara M, Hirano M, Nanko S, Akahane A, Ueno M, Kaneko N, Watanabe Y, Someya T, Hashimoto K, Iyo M, Itokawa M, Arai M, Nankai M, Inada T, Yoshida S, Kunugi H, Nakamura M, Iijima Y, Okazaki Y, Higuchi T, Yoshikawa T. Preliminary genome-wide association study of bipolar disorder in the Japanese population. Am J Med Genet B Neuropsychiatr Genet. 150B(8):1110-7, 2009.
Anitha A, Nakamura K, Yamada K, Iwayama Y, Toyota T, Takei N, Iwata Y, Suzuki K, Sekine Y, Matsuzaki H, Kawai M, Thanseem I, Miyoshi K, Katayama T, Matsuzaki S, Baba K, Honda A, Hattori T, Shimizu S, Kumamoto N, Kikuchi M, Tohyama M, Yoshikawa T, Mori N. Association studies and gene expression analyses of the DISC1-interacting molecules, pericentrin 2 (PCNT2) and DISC1-binding zinc finger protein (DBZ), with schizophrenia and with bipolar disorder. Am J Med Genet B Neuropsychiatr Genet. 150B(7):967-76, 2009.
Iwata K, Matsuzaki H, Takei N, Manabe T,Mori N. :Animal models of autism: an epigenetic and environmental viewpoint.Journal of Central Nervous System Disease,2, 37-44.2010(*Correspondence author)
Wakuda T, Suzuki A, Hasegawa M, Ichikawa D, Yamasue H. Acute agranulocytosis when switching from risperidone to paliperidone. Aust N Z J Psychiatry. 2019 Jan 14:4867418821441. doi: 10.1177/0004867418821441.
講演・学会発表等
2018
Hidenori Yamasue "Development of oxytocin as a novel therapeutic for autism spectrum core symptoms" Cold Spring Harbor Asia. Sozhou, China, Sep 17-21, 2018.
Hidenori Yamasue "Genes and effects of oxytocin on autistic social behaviors and their neural underpinings" Understanding the Neuroregulatory Actions of Oxytocin and its Potential Clinical Applications. Sicily, Italy, MAY 22-27, 2018.
Hidenori Yamasue "Applications of multimodal neuroimaging and pharmacogenetics to develop oxytocin as a novel therapeutic for autism spectrum core symptoms" in a symposia: "Emerging therapeutic targets against autism spectrum disorder." 18th World Congress of Basic and Clinical Pharmacology, 4th July, 2018, Kyoto, Japan.
Wakuda T, Yokokura M, Nakaizumi K, Kato Y, Kameno Y, Futatsubashi M, Yoshikawa E, Magata Y, Ouchi Y, Yamasue H, Takei N: A pilot study of [11C] (R)-MeQAA PET brain imaging analysis of alpha 7 nicotinic acetylcholine receptors availability in schizophrenia. Schizophrenia International Research Congress. 2018.4. Florence, Italy
Yokokura M, Yamasue H, Ouchi H. "Activated microglia in attention-deficit/hyperactivity disorder: a positron emission tomography study." The world federation of society of biological psychiatry (WFSBP) 2018, JAPAN, 2018/9/7-9.
Yasuhiko Kato, Hitoshi Kuwabara, Takashi Okada, Toshio Munesue, Miho Kuroda, Masaki Kojima, Walid Yassin, Seico Benner, Yosuke Eriguchi, Yosuke Kameno, Chihiro Murayama, Teruko Yuhi, Norio Ozaki, Hirotaka Kosaka, Hidenori Yamasue "Metabolomic characteristics and oxytocin's efficacy on them in autism spectrum disorder" Cold Spring Harbor Asia. Sozhou, China, Sep 17-21, 2018.
Chihiro Murayama, Hitoshi Kuwabara, Takashi Okada, Toshio Munesue, Miho Kuroda, Masaki Kojima, Walid Yassin, Seico Benner, Yosuke Eriguchi, Yosuke Kameno, Yasuhiko Kato, Teruko Yuhi, Junichi Masuda, Norio Ozaki, Hirotaka Kosaka, Hidenori Yamasue "Involvement of the kynurenine pathway in the effect of oxytocin on adult males with ASD: an exploratory study" Cold Spring Harbor Asia. Sozhou, China, Sep 17-21, 2018.
Hidenori Yamasue "Development of novel therapeutics for autism spectrum core symptoms utilizing oxytocin, neuroimaging, and genetic analyses." 28th JSBN, Social Neural Networks Research Unit Kickoff Symposium. Tsukuba, Japan, 3rd Mar, 2018.
Hidenori Yamasue "Applications of multimodal neuroimaging indices and genetics to develop oxytocin as a novel therapeutic for autism spectrum disorder" The 4th Symposium of Neuroscience Network in Kobe 16th Feb, 2018, Kobe, Japan.
Yokokura M, Terada T, Bunai T, Nakaizumi K, Yasuhiko Kato, Futatsubashi M, Yoshikawa E, Yamasue H, Ouchi Y: "Activated microglia increased in anorexia nervosa: a [11C]DPA713 PET study" The 17th conference of peace through mind/brain science, 2018.
2017
山末英典 "Oxytocin-related genotypes and effects of oxytocin on autistic social behaviors and their neural underpinings" Plenary lecture in International Autism Conference Tokyo 2017、2017年10月15日、一ツ橋.
Hidenori Yamasue. "Development of intranasal oxytocin as treatment of autism spectrum disorder utilizing brain functional imaging." Symposium on Oxytocin and Social Behavior, 4th July, 2017, Hamamatsu, Japan.
山末英典「Human Brain Structural Change Related to Acute Single Exposure to Sarin」GHSAG Chemical Event Symposium、2017年11月20日、大阪
Yokokura M, Terada T, Bunai T, Nakaizumi K, Yasuhiko Kato, Futatsubashi M, Yoshikawa E, Ouchi Y: "Increased microglial activation in anorexia nervosa: a [11C]DPA713 PET study" Neuroscience 2017, Nov.11-15,2017.
2016
Hidenori Yamasue "An application of neuroimaging to satisfy unmet medical needs associated with autism spectrum disorders" JSBN-RIEMS joint Symposium "International educational symposium of prosocial behavior", 25th JSBN, Sep 14, 2016, Atami, Shizuoka
Yokokura M, Terada T, Bunai T, Nakaizumi K, Takebayashi K, Futatsubashi M, Yoshikawa E, Ouchi Y: "Reduced serotonin transporter availability in anorexia nervosa: a [11C]DASB PET study" Neuroscience 2016, Nov.12-16,2016. USA.
2015
Yokokura M:"A comparison study of microglial activation in aging and dementia between first- and second-generation TSPO PET tracers: [11C]PK11195 and [11C]DPA713.", Neuroscience2015, 平成27年10月17~23日、Chikago, USA.
2013
Yokokura M:Depiction of microglial activation in the living human brain by different TSPO tracers, Neuroscience2013, November 2013, San Diego, USA.
2012
Iwata K, Matsuzaki H, Wakuda T, Takei N., Mori N.: Alteration of the expression balance of hnRNP C1 and C2 changes the expression of myelination- and schizophrenia-related genes in the human neuroblastima cell line. 3rd Schizophrenia International Research Society Conference. April 14-18, 2012, Florence, Italy.
Wakuda T., Iwata K., Suzuki K., Takei N., Mori N.: Alteration of several schizophrenia candidate genes expression in medial prefrontal cortex in perinatal apsyxia rodent model. 3rd Schizophrenia International Research Society Conference. April 14-18, 2012, Florence, Italy.
Yoshihara Y, Sugihara G, Ishizuka A, Yogo H, Nakamura K, Sugiyama T, Matsumoto K, Tsuchiya KJ, Suzuki K, Takei N, Tsujii M, Mori M.:Glutamate dysfunction in the basal ganglia of autism spectrum disorders: an MRS study. The 11th International Meeting for Autism Research, May 17-19, 2012. Toronto,Canada.
2011
Suzuki K:Molecular Imaging in Methamphetamine Abuse. Society of Biological Psychiatry 66th Annual meeting 2011 San Francisco, USA
Matsuzaki H, Iwata K, Tsuchiya KJ, Itoh H, Mori N:VLDL-specific hypolipidemia pattern in human subjects with autism and autistic rodent models. The 7th World Congress on Developmental Origins of Health and Disease, September 18-21 2011. Portland, USA
2010
Nakamura K, Ouchi Y, Tsujii M, Tsuchiya KJ, Sugihara G, Iwata Y, Suzuki K, Matsuzaki H, Suda S, Sugoyama T, Takei N, Mori N. : Brain serotonin and dopamine transporter bindings in adults with autism. 9thAnnual International Meeting For Autism Reserch,May 20, 2010. Philadelphia, USA
Nakamura K,Ouchi Y, Tsujii M, Tsuchiya KJ, Sugihara G, Iwata Y, Suzuki K, Matsuzaki H, Suda S, Sugoyama T, Takei N, Mori N. : Brain serotonin and dopamine transporter bindings in adults with autism. 40thAnnual Meeting of The Society for Neuroscience, November, 2010, San Diego, USA.
Wakuda T, Suda S, Iwata K, Suzuki K, Mori N, Takei N. : Alteration of AKT1 and Neuregulin-1 gene expression in frontal cortex and dentate gyrus may be associated with schizophrenia: perinatal asphyxia model in rat.Schizophrenia International Research Congress. 2010Apr.Florence, Italy.
Tsuchiya KJ, Matsumoto K, Takahashi S, Mori T, Takabayashi R, Suzuki Y, Sato R, Narumiya M, Seno Y, Suda S, Matsuzaki H, Suzuki K, Mori N, Takei N. : the HBC Study Team. Early- and late-onset postpartum depression and the associated risk factors: the HBC Study. Longitudinal and Life Course Studies 1 (suppl 3): 374, October13-15, 2010, Paphos, Cyprus.
Matsuzaki H, Iwata K, Suda S, Tsuchiya KJ, Suzuki K, NakamuraK, Tsujii M, Takei N, Mori N. Dyslipidemia in male patients with high-functioning autism. The 9thannual International Meeting for Autism Research, May 20, 2010, Philadelphia, USA
Matsuzaki H, Fujita-Shimizu A, Iwata K, Suda S, Shimmura C, Kameno Y, Mori N. :Serum adipokine levels in children with autism. The Society for Neuroscience 40th annual meeting, November 16, 2010, San Diego, USA.
Iwata K, Matsuzaki H, Izumo N, Ichitani, Y, Mori N. : VLDLR overexpression rat:evaluationas an animal model of autism.Society for neuroscience ,November13-16,2010,San Diego ,USA.
Shimmura C, Suda S, Tsuchiya K.J, Hashimoto K, Ohno K, Matsuzaki M, Iwata K, Kameno Y, Nakamura K, Takei N, Mori N.:Dysregulation of glutamatergic biosynthetic pathway in subjects with autism. The Society for Neuroscience 40th annual meeting, November 16,2010, San Diego, USA.
2009
Nakamura K, Miyachi T, Ayyappan A, Tsujii M, Suda S, Thanseem I, Tsuchiya K, Matsuzaki H,Yamada K, Iwayama}; Y, Toyota T, Hattori E, Sugiyama T, Takei N, Yoshikawa T, Mori N. Genetic and Expression Analyses of Serotonergic Factors in Autism. 8thAnnual International Meeting For Autism Research,May, 2009. Chicago, USA
2008
Yoshihara Y, Sugihara G, Suckling J, Isoda H, Sakahara H,Mori N, Takei N. : Voxel-based structural MRI study of patients with early-onset schizophrenia. The 1st Schizophrenia International Research Society Conference, Venice, Italy.
Nakamura K, Matsuzaki H, Tsujii M, Ayyappan A, Yamada K, Suda S, Iwayama Y, Miyachi T, Tsuchiya K, Sugiyama T, Takei N, Yoshikawa T, Mori N. : Genetic analyses of serotonergic factors in autism. 7thAnnual International Meeting For Autism Research, London.