Education
6:00 pm- Tuesday, Oct 18th, 5:30 pm- Wednesday, Oct 19th
Poster Session 1---Plasminogen, Plasminogen Activators, Plasmin
PS1-01--Small Angle X-ray Scattering (SAXS) Studies of Human Plasminogen
Adam Juinn H. Quek, Ruby HP. Law, Nathan P. Cowieson, Nigel Kirby, James C. Whisstock
PS1-02--Identification of novel substrates of plasmin on endothelial cells
Nanami Kimura, Makoto Hasegawa, Nobuo Nagai
PS1-03--Differential expression of the plasminogen receptor Plg-RKT in monocyte and macrophage subsets - possible functional consequences in atherogenesis
Barbara Thaler, Philipp J. Hohensinner, Johanna Baumgartner, Nagyung Baik, Konstantin K. Krychtiuk, Gerald Maurer, Kurt Huber, Walter Speidl, Robert J. Parmer, Lindsey A. Miles, Johann Wojta
PS1-04--Different effect of tissue- and urokinase-type plasminogen activators in whole blood and artificial blood-free system
Ivan Budnik, Boris Shenkman, Yulia Einav, Uriel Martinowitz
PS1-05--Thrombolytic and side effects of combinations of tissue plasminogen activator and recombinant staphylokinase in vitro
Lilia I. Mukhametova, Roza B. Aisina, Karina B. Gershkovich, Sergei D. Varfolomeyev
PS1-06-Properties of prourokinase-dendrimer conjugates: stability in human plasma, plasminogen activator and thrombolytic activities in vitro
Roza B. Aisina, Lilia I. Mukhametova, Elizaveta M. Ivanova, Karina B. Gershkovich, Sergei D. Varfolomeyev
PS1-07--Mutual catalysis of plasmin and urokinase generation and the threshold effects in the fibrinolytic regulatory system
Philipp V. Kuznetsov, Konstantin G. Guria
Poster Session 2---TAFI, PAI-1, Regulation of Fibrinolysis
PS2-01 (OS1-01)--Lysine 42, 43, 44 and Arginine 12 within the Activation Peptide of Thrombin Activable Fibrinolysis Inhibitor Contribute to its Activation by the Thrombin-Thrombomodulin Complex in a Cooperative Fashion
Paul Y. Kim, Chengliang Wu, James C. Fredenburgh, Jeffrey I. Weitz, Ann Gils, Paul J. Declerck
PS2-02 (OS1-03)--Carboxypeptidase U (CPU, CPB2 or TAFIa) generation during experimental embolic stroke in rat
Dorien Leenaerts, Jean-Philippe Desilles, Joachim C. Mertens, Stéphane Loyau, Martine Jandrot-Perrus, Mikael Mazighi, Dirk Hendriks
PS2-03--Thrombin-activated Fibrinolysis Inhibitor in Chronic Thromboembolic Pulmonary Hypertension
Noboru Yaoita, Kimio Satoh, Taijyu Satoh, Yoshihiro Fukumoto, Hiroaki Shimokawa
PS2-04--Coagulation-dependent initiation of fibrinolysis takes place on the surface of activated platelets, and is targeted by TAFI
Tomasz Brzoska, Seiichiro Suzuki, Yuko Suzuki, Hideto Sano, Martyna Tomczyk, Hiroki Tanaka, Tetsumei Urano
PS2-05--TAFIa inhibitor DS-1040 ameliorated dextran sulfate sodium-induced ulcerative colitis in rats
Kengo Noguchi, Yusuke Ito, Yoshiyuki Morishima, Kyoji Yamaguchi
PS2-06 (OS1-04)--Structural studies of the effect of inhibitory antibody fragments on plasminogen activator inhibitor 1 (PAI-1)
Machteld Sillen, Stephen D. Weeks, Xiaohua Zhou, Sergei V. Strelkov, Paul J. Declerck
PS2-07 (OS4-01)--Proteolytic activity of circulating microparticles from ischemic stroke patients revealed by single particle laser-scanning confocal microscopy
Sara Martinez De Lizarrondo, Aurélien Briens, Jérôme Parcq, Joan Montaner, Denis Vivien, Maxime Gauberti
PS2-08 (OS4-02)--Lipid rafts, αIIbβ3 and transglutaminase activity are all required for the translocation of factor XIII-A from the activated platelet membrane into the fibrin network
Joanne L. Mitchell, Nicola J. Mutch
PS2-09 (YIA-3)--Plasminogen Activator Inhibitor 1 Associates with the Activated Platelet Membrane via a Fibrin and αIIbβ3 Specific Mechanism
Gael B. Morrow, Nicola J. Mutch, Claire S. Whyte
PS2-10 (OS4-04)--Optimising the degradation of NETs to destabilise fibrin clot structure and promote fibrinolysis
Matthew Locke, Robert Francis, Colin Longstaff
Poster Session 3---Plasminogen Activation System and Neuroscience
PS3-01--Roles of tissue plasminogen activator/ plasmin system on the functional recovery and histological repair in ischemic stroke in mice
Yasuki Matano, Yusuke Sakai, Chiemi Ohmori, Yasuhiro Suzuki, Kazuo Umemura, Nobuo Nagai
PS3-02 (OS9-03)--Evidence That Matrix Metalloproteinase-9 Mediates the Harmful Effects of Alpha2-Antiplasmin in Ischemic Stroke
Satish Singh, Aiilyan K. Houng, Guy L. Reed
PS3-03 (YIA-4)--The neuronal tPA contributes to the physiological corticogenesis by promoting NMDA receptors signaling in the glial radial fibers
Nolwenn Pasquet, Mikaël Naveau, Sara Douceau, Flavie Lesept, Yannick Hommet, Laurent Lebouvier, Denis Vivien, Isabelle Bardou
PS3-04--Migration of neural cells, axon growth and branching depend on urokinase and urokinase receptor activity
Ekaterina V. Semina, Kseniya A. Rubina, Karina D. Rysenkova, Vsevolod A. Tkachuk
PS3-05 (YIA-5)--Tissue plasminogen activator (tPA) null mice decrease dopaminergic loss and increase behavioral recovery in a murine PD model
Daniel Torrente, Gerald P. Schielke, Kagya A. Amoako, Mark Warnock, Daniel A. Lawrence
PS3-06 (OS8-02)--The type-4 desintegrin and metalloproteinase with thrombospondin motifs (ADAMTS-4): a new actor in the central nervous system myelination processes
Mathilde Pruvost, Matthieu Lepine, Camille Leonetti, Eric Maubert, Evelyne Emery, Fabian Docagne, Denis Vivien
PS3-07--Multilinage-differentiating stress-enduring (Muse) cells migrate a long distance to the glioma in the mouse brain
Tomohiro Yamasaki, Shohei Wakao, Mari Dezawa, Hiroki Namba
PS3-08 (YIA-2)--Does the Plasminogen Activation System Contribute to Immunosuppression after Traumatic Brain Injury?
Dominik F. Draxler, Maria Daglas, Gryselda Hanafi, Adam Galle, Amanda E. Au, Magdalena Plebanski, Maithili Sashindranath, Robert L. Medcalf
Poster Session 4---Plasminogen Activation System and Tissue Remodeling
PS4-01 (OS8-03)--Comprehensive Modeling for Capillary Morphometry and Blood Flow in Wildtype and tPA-/- Mice
Randy C. Stevenson, Tamara K. Stevenson, Linda Fredriksson, Daniel A. Lawrence
PS4-02 (OS5-06)--Tissue Plasminogen Activator promotes the formation of intracerebral aneurisms
Romain Goulay, Paul-Emile Labeyrie, Sara De Lizarondo Martinez, Eric Maubert, Cyrille Orset, Denis Vivien
PS4-03--MMP-7-catalyzed processing of HAI-1 induces cancer cell aggregation and promotes cancer metastasis
Tomohiro Ishikawa, Yayoi Kimura, Hisashi Hirano, Shouichi Higashi
PS4-04--Regulation of migration and protease secretion in MSC and monocytic cells treated by inflammatory and tumor-associated factors
Ekaterina Zubkova, Irina Beloglazova, Yelena Parfyonova, Mikhail Menshikov
PS4-05--Lignous conjonctivitis : plasminogen deficiency, what else?
Marie-Charlotte Bourrienne, Dorothée Faille, Stéphane Loyau, Martine Jandrot-Perrus, Eric Gabison, Nadine Ajzenberg
PS4-06--The effect of dietary food on the development of abdominal aortic aneurysm
Hirona Kugo, Nobuhiro Zaima, Youhei Mouri, Hiroki Tanaka, Tetsumei Urano, Naoki Unno, Tatsuya Moriyama
PS4-07--The effect of high fat diet on development of abdominal aortic aneurysm
Keisuke Hashimoto, Hirona Kugo, Nobuhiro Zaima, Tatsuya Moriyama
Poster Session 5---Novel Strategies to Evoke Fibrinolysis
PS5-01--Temporal blockade of thrombin activity enhance secondary fibrinolysis
Asuka Sakata, Kinya Seo, Satoshi Nishimura
PS5-02 (YIA-1)--A Novel Thrombolytic Drug based on Thrombin Cleavable Microplasminogen Coupled to a Single-Chain Antibody Specific for Activated GPIIb/IIIa
Thomas Bonnard, Zachary Tennant, Ruchi Kanojia, Karen Alt, Shweta Jagdale, Lok Soon Law, Sheena Rigby, Karlheinz Peter, Christoph Hagemeyer
PS5-03 (OS11-01)--Evaluation of the in vivo action of SMTP-7, a novel small-molecule anti- inflammatory thrombolytic for ischemic stroke
Eriko Suzuki, Yudai Kunikiyo, Naoki Matsumoto, Hironobu Sawada, Naoko Nishimura, Keiko Hasegawa, Keiji Hasumi
PS5-04--Antithrombotic effect of oral administration of brown seaweed extract
Toshinori Yasuzawa, Kana Shintaku, Moica Ozawa, Shigeru Ueshima
PS5-05--Perfumes Induced t-PA Activity from Human Cells
Hiroyuki Sumi, Sawa Naito, Tadanori Ohsugi, Masatoshi Imai, Hisaya Mizote, Masugi Maruyama
PS5-06--Nattokinase (Powder of extract natto culture mixture) for health foods
Soichiro Takagaki, Takaaki Ito, Yasuhide Yanagisawa, Hiroyuki Sumi
PS5-07--"Germ-Natto,"a New Functional Food in the World
Hiroyuki Sumi, Hirokazu Kimura, Yuko Sato, Chieko Yatagai, Etsuo Yoshida
PS5-08--Grape intake enhances plasma fibrinolysis and reduces thrombin generation: Role of circulating procoagulant microparticles
Concetta T. Ammollo, Fabrizio Semeraro, Rosa A. Milella, Donato Antonacci, Nicola Semeraro, Mario Colucci
Poster Session 6---Diagnostic Markers
PS6-01--Diagnosis and treatment of inherited platelet function disorders: Guidance from the THROMKID study group of GTH
Ralf Knoefler, Werner Streif
PS6-02--Endocan concentration in hypertensive patients with coronary artery disease
Dominika Musialowska, Edyta Zbroch, Ewa Koc-Zorawska, Hanna Bachorzewska-Gajewska, Slawomir Dobrzycki, Jolanta Malyszko
PS6-03--VAP-1 in hemodialysis and hemodiafiltration patients; effect of single hemodialysis session on VAP-1 levels in regards to type of anticoagulant
Ewa Koc-Zorawska, Jolanta Malyszko, Jacek S. Malyszko, Marcin J. Zorawski
PS6-04--Hemodialysis session is associated with a significant rise in serum endocan, a novel molecule derive from endothelium
Marcin J. Zorawski, Jolanta Malyszko, Jacek S. Malyszko, Ewa Koc-Zorawska