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原著論文

  1. Clinical significance of urokinase-type plasminogen activator (uPA) in invasive cervical cancer of the uterus.Sugimura M., Kobayashi H., Kanayama N., Terao T. : Gynecol Oncol. 46:33-6, 1992.
  2. Characterization and clinical evaluation of tumor-associated antigen CA54/61 identified by monoclonal antibodies MA54 and MA61 in epithelial ovarian cancer. Kobayashi H., Ohi H.,Sugimura M., Shinohara H., Terao T.: Gynecol Oncol. 47:328-36, 1992.
  3. Inhibition of in vitro ovarian cancer cell invasion by modulation of urokinase-type plasminogen activator and cathepsin B. Kobayashi H., Ohi H.,Sugimura M., Shinohara H., Fujii T., Terao T.: Cancer Res. 52:3610-4, 1992.
  4. Monoclonal antibodies MA54 and MA61 as potential reagents in the prognosis of patients with ovarian cancer. Kobayashi H., Ohi H.,Sugimura M., Shinohara H., Terao T. : Gynecol Oncol. 49:80-5, 1993.
  5. Saturation of tumour cell surface receptors for urokinase-type plasminogen activator by amino-terminal fragment and subsequent effect on reconstituted basement membranes invasion. Kobayashi H., Ohi H., Shinohara H.,Sugimura M., Fujii T., Terao T., Schmitt M., Goretzki L., Chucholowski N., Janicke F. et al.: Br J Cancer. 67:537-44, 1993.
  6. Plasmin modulators, aprotinin and anti-catalytic plasmin antibody, efficiently inhibit destruction of bovine vascular endothelial cells by choriocarcinoma cells. Sugimura M., Kobayashi H., Terao T.:cells. Gynecol Oncol. 52:337-46, 1994.
  7. Annexin V as a probe of the contribution of anionic phospholipids to the procoagulant activity of tumour cell surfaces.Sugimura M., Donato R., Kakkar V.V., Scully M.F.: Blood Coagul Fibrinolysis 5:365-73, 1994.
  8. Effects of urinary trypsin inhibitor on the invasion of reconstituted basement membranes by ovarian cancer cells. Kobayashi H., Fujie M., Shinohara H., Ohi H.,Sugimura M., Terao T. : Int J Cancer. 57:378-84, 1994.
  9. Urinary trypsin inhibitor (UTI) and fragments derived from UTI by limited proteolysis efficiently inhibit tumor cell invasion. Kobayashi H., Shinohara H., Ohi H.,Sugimura M., Terao T., Fujie M.: Clin Exp Metastasis. 12:117-28, 1994.
  10. Role of activated protein C in facilitating basement membrane invasion by tumor cells. Kobayashi H., Moniwa N., Gotoh J.,Sugimura M., Terao T.: Cancer Res.54:261-7, 1994.
  11. Anticoagulant activity in non-immunoglobulin fraction from plasma of patients with antiphospholipid syndrome.Sugimura M., Su F., Kanayama N., Kobayashi H., Kobayashi T., Terao T.: Semin Thromb Hemost. 24:473-7, 1998.
  12. Detection of decreased response to activated protein C during pregnancy by an endogenous thrombin potential-based assay.Sugimura M., Kobayashi T., Kanayama N., Terao T.: Semin Thromb Hemost. 25:497-502, 1999.
  13. Detection of marked reduction of sensitivity to activated protein C prior to the onset of thrombosis during puerperium as detected by endogenous thrombin potential-based assay.Sugimura M., Kobayashi T., Kanayama N., Terao T.: Thromb Haemost. 82:1364-5, 1999.
  14. Annexin V inhibits phosphatidylserine-induced intrauterine growth restriction in mice.Sugimura M., Kobayashi T., Shu F., Kanayama N., Terao T. : Placenta. 20:555-60,1999.
  15. Upregulation of thrombomodulin antigen levels in U937 cells by combined stimulation with estradiol-17beta and vitamin K2 (menaquinone 4). Nishiguchi T., Kobayashi T.,Sugimura M., Kobayashi H., Terao T. :Semin Thromb Hemost. 25:509-17, 1999.
  16. Coagulation/fibrinolysis disorder in patients with severe preeclampsia. Kobayashi T., Tokunaga N.,Sugimura M., Suzuki K., Kanayama N., Nishiguchi T., Terao T. : Semin Thromb Hemost. 25:451-4, 1999.
  17. Induction of preeclampsia like phenomena by stimulation of sympathetic nerve with cold and fasting stress. Khatun S., Kanayama N., Belayet H.M., Masui M.,Sugimura M., Kobayashi T., Terao T.:Eur J Obstet Gynecol Reprod Biol. 86:89-97, 1999.
  18. Dehydroepiandrosterone sulphate promotes hyaluronic acid-induced cervical ripening in rabbits. Belayet H.M., Kanayama N., Khatun S., Tokunaga N.,Sugimura M., Yamashita M., Kobayashi T., Terao T. : Hum Reprod. 14:1361-7, 1999.
  19. A new treatment of severe pre-eclampsia by long-term epidural anaesthesia. Kanayama N., Belayet H.M., Khatun S., Tokunaga N.,Sugimura M., Kobayashi T., Terao T.: J Hum Hypertens. 13:167-71, 1999.
  20. Imunohistochemical study of annexin V expression in placentae of preeclampsia. Shu F.,Sugimura M., Kanayama N., Kobayashi H., Kobayashi T., Terao T.: Gynecol Obstet Invest. 49:17-23, 2000.
  21. Dilatation of the left renal vein in preeclampsia. Tokunaga N., Kanayama N.,Sugimura M., Kobayashi T., Terao T.: J Matern Fetal Med. 9:356-9, 2000.
  22. Left renal vein and early-onset preeclampsia. Kobayashi T., Tokunaga N.,Sugimura M., Kanayama N., Terao T.:Thromb Haemost. 84:930-1, 2000.
  23. Intraplacental coagulation in intrauterine growth restriction: cause or result Sugimura M., Ohashi R., Kobayashi T., Kanayama N.: Semin Thromb Hemost. 27:107-13, 2001.
  24. Activated protein C prevents development of phosphatidylserine-induced intrauterine growth restriction in mice. Shu F.,Sugimura M., Kobayashi H., Kobayashi T., Kanayama N.: Semin Thromb Hemost. 27:99-105, 2001.
  25. Predictive values of coagulation/fibrinolysis parameters for the termination of pregnancy complicated by severe preeclampsia. Kobayashi T., Tokunaga N.,Sugimura M., Kanayama N., Terao T.: Semin Thromb Hemost. 27:137-41, 2001.
  26. Anti-macrophage inhibitory factor antibody inhibits PMSG-hCG-induced follicular growth and ovulation in mice. Matsuura T.,Sugimura M., Iwaki T., Ohashi R., Kanayama N., Nishihira J.: Am J Assist Reprod Genet. 19:591-595, 2002
  27. Coagulation index to distinguish severe preeclampsia from normal pregnancy. Kobayashi T, Suminoto K, Tokunaga N,Sugimura M, Nishiguchi T, Kanayama N, Terao T.Semin Thromb Hemost. 28: 495-499, 2002
  28. Anticholinergics induce eclamptic seizures. Kobayashi T.,Sugimura M., Tokunaga N., Naruse H., Nishiguchi T., Kanayama N., Terao T. Semin Thromb Hemost. 28: 511-514, 2002
  29. Deficiency in p57Kip2 expression induces preeclampsia-like symptoms in mice. Kanayama N., Takahashi K., Matsuura T.,Sugimura M., Kobayashi T., Moniwa N., Tomita M.,Nakayama K. Mol Hum Repro 8: 1129-1135, 2002
  30. Recombinant adenovirus vector bearing antisennse macrophage migration inhibitory factor cDNA prevents acute lipopolysaccharide-induced liver failure in mice. Iwaki T,Sugimura M, Nishihira J, Matsuura T, Kobayashi T, Kanayama N.: Lab Invest 83:561-570, 2002
  31. Estrogen administration enhances thrombin generation in rats. Ohashi R,Sugimura M, Kanayama N. Thromb Res.112:325-8. 2003
  32. Alteration of integrins under hypoxic stress in early placenta and choriocarcinoma cell line BeWo. Iwaki T, Yamamoto K, Matsuura T,Sugimura M,Kobayashi T, Kanayama N. Gynecol Obstet Invest.57:196-203. 2004.
  33. Exogenous vascular endothelial growth factor can induce preeclampsia-like symptoms in pregnant mice.Murakami Y,Kobayashi T,Omatsu K,Suzuki M,Ohashi R,Matsuura T,Sugimura M,Kanayama N. Semin Thromb Hemost. 31:307-13. 2005
  34. Phosphatidylserine/phosphatidylcholine microvesicles can induce preeclampsia-like changes in pregnant mice. Omatsu K,Kobayashi T,]Murakami Y,Suzuki M,Ohashi R,Sugimura M,Kanayama N.Semin Thromb Hemost.;31:314-20. 2005
  35. Sensitivity to activated protein C in patients with deep vein thrombosis during early puerperium period. Ohashi R,Sugimura M,]Kawamura T,Tamura N,Kanayama N. Acta Obstet Gynecol Scand.; 84:799-801. 2005
  36. Measurement of placental oxygenation by transabdominal near-infrared spectroscopy. Kawamura T, Kakogawa J, Takeuchi Y, Takani S, Kimura S, Nishiguchi T,Sugimura M, Sumimoto K, Kanayama N: Am J Perinatol 24: 161-166, 2007.
  37. Molecular basis of antithrombin deficiency in four Japanese patients with antithrombin gene abnormalities including two novel mutations.
  38. Kyotani M, Okumura K, Takagi A, Murate T, Yamamoto K, Matsushita T, Sugimura M, Kanayama N, Kobayashi T, Saito H, Kojima T.Am J Hematol. 82: 702-705, 2007
  39. Prostaglandin E2 receptor EP4-selective antagonist inhibits lipopolysaccharide-induced cervical ripening in rabbits.Fukuda Y,Sugimura M,Suzuki K, Kanayama N: Acta Obstet Gynecol Scand. 86(11) :1297-1302, 2007
  40. Chorangiosis and placental oxygenation.Suzuki K, Itoh H, Kimura S, Sugihara K, Yaguchi C, Kobayashi Y, Hirai K, Takeuchi K, Sugimura M,Kanayama N.Congenit Anom.49(2):71-6. 2009
  41. A case of a huge placental lake; prenatal differential diagnosis and clinical management.Muramatsu K, Itoh H, Yamasaki T, Nakamura Y, Kobayashi Y, Hirai K, Suzuki K, Sugihara K,Sugimura M, Kanayama N. J Obstet Gynecol Res 36: 165-169, 2010:
  42. A rapid activated protein C sensitivity test as a diagnostic marker for a suspected venous thromboembolism in pregnancy and puerperium Hirai K,Sugimura M, Ohashi R, Suzuki K, Itoh H, Sugihara K, Kanayama N. Gynecol Obstet Invest. 72; 55-62, 2011
  43. Heparin/heparan sulfate/CD44-v3 enhances cell migration in term placenta-derived immortalized human trophoblast cells. Suga N.Sugimura M, Kshiishi T, Yorifuji T, Makino S, Takeda S. Biol reprod. 134; 1-8 2012