教育

Education

研究業績

総説

永田 年、小出幸夫:結核菌に対するT細胞誘導ワクチンの試み. 日本細菌学雑誌, 65 (2), 309-324, 2010.

Nagata T, Koide Y: Induction of specific CD8+ T cells against intracellular bacteria by CD8+ T-cell-oriented immunzation approaches. J Biomed Biotechnol, 2010, Article ID 764542.

著書

永田 年:食物アレルギーを予防する機能. 西村敏英・浦野哲盟(編), 食品の保健機能と生理学, アイ・ケイコーポレーション (pp. 139-153, 2015年3月30日).

Nagata T, Koide Y: Identification of T-cell epitopes of Mycobacterium tuberculosis with biolistic DNA vaccination. In Sudowe S, Reske-Kunz AB (eds.) Biolistic DNA Delivery: Methods and Protocols, Springer, 285-303, 2013, ISBN 978-1-62703-109-7.

Nagata T, Koide Y:Immune responses againstMycobacterium tuberculosisand the vaccine strategies. In Cardona P-J (Edit.): Understanding tuberculosis - Analyzing the origin ofMycobacterium tuberculosispathogenicity, InTech, 2012, ISBN 978-953-307-942-4.

Nagata T, Koide Y: Anti-infective vaccine strategies. In Liu D (ed.) Handbook of Listeria monocytogenes, p. 449-480, CRC Press, Boca Raton, Florida, 2008.

原著論文

2020年

Yokomizo T, Kanno K, Yamagishi A, Nagata T: Perception of mutual aid and its related factors: a study of Japanese high school students. BioSci Trends, DOI: 10.5582/bst.202003309, 2020.

Tanaka K, Enomoto N, Uehara M, Furuhashi K, Sakurai S, Yasui H, Kanayama M, Hozumi H, Suzuki Y, Fujisawa T, Inui N, Nakamura Y, Nagata T, Suda T: Development of a novel T cell-oriented vaccine using CTL/Th hybrid epitope long peptide and biodegradable microparticles, against an intracellular bacterium. Microbiol Immunol, 64, 666-678, 2020.

小山順子, 永田 年: 循環器病棟看護師の歯周炎に関する知識・認識の現状. 日本口腔ケア学会誌, 15(1), 17-23, 2000.

2019年

Seto S, Morimoto K, Yoshida T, Hiramatsu M, Hijikata M, Nagata T, Kikuchi F, Shiraishi Y, Kurashima A, Keicho N: Proteomic profiling reveals the archtecture of granulomatous lesions caused by tuberculosis and Mycobacterium avium complex lung disease. Front Microbiol, 10 (3081), 2019.

2018年

Yamashita S, Suzuki T, Iguchi K, Sakamoto T, Tomita K, Yokoo H, Sakai M, Misawa H, Hattori K, Nagata T, Watanabe Y, Matsuda N, Yoshimura N, Hattori Y: Cardioprotective and functional effects of levosimendan and milrinone in mice with cecal ligation and puncture-induced sepsis. Naunyun-Schmiedeberg's Arch Pharmacol, Epub ahead of printing, 2018.

2017年

Tani S, Takano R, Tamura S, Oishi S, Iwaizumi M, Hamaya Y, Takagaki K, Nagata T, Seto S, Horii T, Kosugi I, Iwashita T, Osawa S, Furuta T, Miyajima H, Sugimoto K: Digoxin attenuates murine experimental colitis by downregulating Th17-related cytokines. Inflamm Bowel Dis, 23(5), 726-738, 2017.

Satake Y, Nakamura Y, Kono M, Hozumi H, Nagata T, Tsujimura K, Enomoto N, Fujisawa T, Tokura Y, Matsui T, Yokomura K, Shirai M, Hayakawa H, Suda T: Type-1 polarized dendritic cells are a potent immunogen against Mycobacterium tuberculosis. Int J Tuberc Lung Dis, 21(5), 523-530, 2017

2016年

Oishi S, Takano R, Tamura S, Tani S, Iwaizumi M, Hamaya Y, Takagaki K, Nagata T, Seto S, Horii T, Osawa S, Miyajima H, Sugimoto K: M2 polarization of murine peritoneal macrophages induces regulatory cytokine production and suppresses T-cell proliferation, Immunology, in press.

2015年

Ikeda M, Enomoto N, Hashimoto D, Fujisawa T, Inui N, Nakamura Y, Suda T, Nagata T: Nontypeable Haemophilus influenzae exploits the interaction between protein-E and vitronectin for the adherence and invasion to bronchial epithelial cells. BMC Microbiology, 15:263, 2015.

Matsui Y, Shimatani M, Kuzuhara K, Miyazaki Y, Horiuchi T, Tajima Y, Yano K, Nagata T: Three-year prospective, observational study of central line-associated bloodstream infections in a 600-bed Japanese acute care hospital. Am. J. Infect. Control, 43: 404-408, 2015.

2014年

Seto S, Nagata T, Horii T, Koide Y: Molecular dissection of Mycobacterium tuberculosis-containing phagosomes. Nihon Saikingaku Zasshi, 69 (3): 513-525, 2014 (Japanese).

2013年

Seto, S., Sugaya, K., Tsujimura, K., Nagata, T., Horii, T., Koide, Y.: Rab39a interacts with phosphatidylinositol 3-kinase and negatively regulates autophagy induced by lipopolysaccharide stimulation in macrophages. PLoS One, 8 (12), e83324, 2013.

Hozumi H., Tsujimura K, Yamamura Y, Seto S, Uchijima M, Nagata T, Miwa S, Hayakawa H, Fujisawa T, Hashimoto D, Inui N, Suda T, Chida K, Koide Y: Immunogenicity of dormancy-related antigens in individuals infected with Mycobacterium tuberculosis in Japan. Int. J. Tuberc. Lung Dis., 17 (6): 818-824, 2013.

2012年

Ishih A, Nagata T, Kobayashi F: The course of a primary infection ofPlasmodium yoelii17XL in both 129S1 and IFN-gamma receptor-deficient mice. Parasitol. Res., DOI: 10.1007/s00436-012-2873-2.

Kono M, Nakamura Y, Suda T, Uchijima M, Tsujimura K, Nagata T,GiermaszAS, Kalinski P, Nakamura H, Chida K: Enhancement of protective immunity against intracellular bacteria using type-1 poralized dendritic cell (DC) vaccine. Vaccine, 30, 2633-2639, 2012.

Kato M, Nakamura Y, Suda T, Ozawa Y, Inui N, Seo N, Nagata T, Koide Y, Kalinski P, Nakamura H, Chida K: Enhanced anti-tumor immunity by superantigen-pulsed dendritic cells. Cancer Immunol. Immunother., DOI: 10.1007/s00262-011-1015-5.

2011年

Uto T, Tsujimura K, Uchijima M, Seto S, Nagata T, Suda T, Chida K, Nakamura H, Koide Y: A novel vaccine strategy to induce mycobacterial antigen-specific Th1 responses by utilizing the C-terminal domain of heat shock protein 70. FEMS Immunol. Med. Microbiol., 61, 189-196, 2011.


2010年

Eweda G, Suzuki D, Nagata T, Tsujimura K, Koide Y: Identification of murine T-cell epitopes on low-molecular-mass secretory proteins (CFP11, CFP17, and TB18.5) of Mycobacterium tuberculosis. Vaccine, 28, 4616-4625, 2010.


Suzuki D, Nagata T, Ewda G, Matsumoto S, Matsumoto M, Tsujimura K, Koide Y: Characterization of murine T-cell epitopes on mycobacterial DNA-binding 1 (MDP1) using DNA vaccination. Vaccine, 28, 2020-2025, 2010.


Wang L-X, Nagata T, Tsujimura K, Uchijima M, Seto S, Koide Y: Identification of HLA-DR4-restricted T-cell epitope on MPT51 protein, a major secreted protein derived from Mycobacterium tuberculosis using MPT51 overlapping peptides screening and DNA vaccination. Vaccine, 28, 2026-2031, 2010.


Yamamura Y, Tsujimura K, Seto S, Uchijima M, Hozumi H, Nagata T, Koide Y: Immunogenicity of latency-associated antigens of Mycobacterium tuberculosis in DNA-vaccinated mice. Procedia in Vaccinology, 3, 19-26, 2010.


2009年

Tsujimura K, Ikehara Y, Nagata T, Koide Y, Kojima N: Induction of anti-tumor immune responses with oligomannose-coated liposomes targeting to peritoneal macrophages. Procedia in Vaccinology, 1, 127-134, 2009.


2008年

Nagata T, Aoshi T, Uchijima M, Koide Y: In vivo hierarchy of individual T-cell epitope-specific helper T-cell subset against an intracellular bacterium. Vaccine, 26, 5123-5127, 2008.


Aoshi T, Nagata T, Suzuki M, Uchijima M, Hashimoto D, Rafiei A, Suda T, Chida K, Koide Y: Identification of HLA-A*0201-restricted T-cell epitope on the MPT51 protein, a major secreted protein derived from Mycobacterium tuberculosis, by MPT51 overlapping peptide screening. Infect Immun, 76, 1565-1571, 2008.

Hashimoto D, Nagata T, Uchijima M, Seto S, Suda T, Chida K, Miyoshi H, Nakamura H, Koide Y: Intratracheal administration of third-generation lentivirus vector encoding MPT51 from Mycobacterium tuberculosis induces specific CD8+ T-cell responses in the lung. Vaccine, 26, 5095-5100, 2008.


Cervantes J, Nagata T, Uchijima M, Shibata K, Koide Y: Intracellular Listeria monocytogenes induces pyroptosis in murine macrophages. Cell Microbiol, 10 (1), 41-52, 2008.

講演・学会発表等